Barry Setlow, Ph.D.

Contact Information

Dr. Barry Setlow
Department of Psychiatry
University of Florida College of Medicine
PO Box 100256
Gainesville, FL 32610-0256
Office: L1-179, MBI Building
Phone: 294-5203 (office), 294-5047 (lab)


Associate Professor, Departments of Psychiatry and Neuroscience, University of Florida College of Medicine, Gainesville, FL

Research Area

My research concerns interactions between drugs of abuse and decision-making.


1994 B.A. in Psychology, Yale University
1998 Ph.D. in Biological Sciences, Department of Psychobiology, University of California, Irvine.  Dr. James L. McGaugh, Chair
1998-2002 Postdoctoral Fellow, Department of Psychological and Brain Sciences, Johns Hopkins University, Laboratory of Dr. Michela Gallagher

Current Research

Much of the research in the Setlow laboratory concerns interactions between decision-making processes and drugs of abuse. In some of their research, they investigate the long-term effects of chronic exposure to drugs of abuse on cognitive outcomes, with a particular focus on different types of decision-making processes (for example, risky and impulsive decision-making) and the neural mechanisms underlying drug-induced alterations in such processes. In other research, they investigate how individual differences in risky and impulsive decision-making predict propensity for future drug use. In all of this research, they use a variety of techniques (e.g., behavioral/cognitive testing, behavioral pharmacology, biochemistry, in vivo electrophysiology) to identify mechanisms that mediate relationships between decision-making and drug abuse, with the ultimate goal of identifying therapeutic targets for both maladaptive decision-making and addiction.

Recent Publications

Mitchell, M. R., Weiss, V. G., Ouimet, D. J., Fuchs, R. A., Morgan, D. & Setlow, B. (2014). Intake-dependent effects of cocaine self-administration on impulsive choice in a delay discounting task. Behavioral Neuroscience. 128, 419-429.

Orsini, C. A., Ginton, G., Shimp, K. G., Avena, N. M., Gold, M. S., & Setlow, B. (2014). Food consumption and weight gain after cessation of chronic amphetamine administration. Appetite. 78, 76-80.

Mitchell, M. R., Weiss, V. G., Beas, B. S., Morgan, D., Bizon, J. L., & Setlow, B. (2014). Adolescent risk taking, cocaine self-administration, and striatal dopamine signaling. Neuropsychopharmacology. 39, 955-962.

Simon N. W., Beas, B. S., Montgomery, K. S., Haberman, R. P., Bizon, J. L., & Setlow, B. (2013). Prefrontal cortical-striatal dopamine receptor mRNA expression predicts distinct forms of impulsivity. European Journal of Neuroscience. 37, 1779-1788.

Simon N. W., Montgomery, K. S., Beas, B. S., Mitchell, M. R., LaSarge, C. L., Mendez, I. A., Baneulos, C., Vokes, C. M., Taylor, A. B., Haberman, R. P., Bizon, J. L., & Setlow, B. (2011). Dopaminergic modulation of risky decision-making. The Journal of Neuroscience. 31, 17460-17470.

Mitchell, M. R., Vokes, C. M., Blankenship, A. L., Simon, N. W., & Setlow, B. (2011). Effects of acute administration of nicotine, amphetamine, diazepam, morphine, and ethanol on risky decision-making in rats. Psychopharmacology. 218, 703-712.