Barry Setlow, Ph.D.
Professor
About Barry Setlow
Barry Setlow received his PhD in 1998 from the University of California, Irvine, where he worked with Jim McGaugh on amygdala-striatal systems involved in consolidation of different forms of learning and memory. He went on to post-doctoral training with Michela Gallagher at Johns Hopkins University, where he continued work on the role of amygdala-striatal systems in different forms of learning, using both behavioral and single-unit electrophysiological recording techniques. From there he moved to a position as an assistant professor at Texas A&M University, where his research focussed on the effects of both acute and chronic exposure to drugs of abuse on cognition, with a particular focus on decision-making. Dr. Setlow joined the Department of Psychiatry in 2010, where he is continuing his research on interactions between drug abuse and decision-making, as well as collaborating with other UF investigators on animal models of age-related cognitive decline.
Accomplishments
UF Research Foundation Professorship
2018-2021
·
University of Florida
Fellow
2017-Current
·
University of California, Irvine Center for the Neurobiology of Learning and Memory
UF Term Professorship
2017-2020
·
University of Florida
Exemplary Teacher
2016
·
University of Florida, College of Medicine
Faculty of Neuroscience Leadership and Service Award
2010
·
Texas A&M University
Young Investigator Travel Award
2008
·
American College of Neuropsychopharmacology
J. L. McGaugh Award for Excellence in Graduate Research
1998
·
Department of Psychobiology, University of California, Irvine
Ralph Waldo Gerard Prize in the History of Neuroscience
1996
·
University of California, Irvine
Teaching Profile
Courses Taught
2014-2025
GMS6780 Addiction: Neuroscience and Trends
2020-2021
GMS6757 Introduction to Alzheimer’s Disease and Related Dementias: Clinical and Mechanistic Principles
2013-2015,2017-2024,2021-2024,2023-2024
GMS6029 Brain Journal Club
2017-2021
GMS6705 Functional Human Neuroanatomy
2018,2022
GMS7980 Research for Doctoral Dissertation
2018,2022-2025
GMS7979 Advanced Research
2018,2023-2025
GMS6022 Principles of Neurophysiology
2015,2023-2025
GMS7794 Neuroscience Seminar
2022
GMS6090 Research in Medical Sciences
2022
GMS6905 Independent Studies in Medical Sciences
2022-2025
GMS6701 Functional and Comparative Neuroanatomy for Professionals
2023-2025
GMS6971 Research for Master’s Thesis
2023
GMS7795 Special Topics in Neuroscience
2024
GMS6025C Statistics for Neuroscientists
Research Profile
Research Interests:
– behavioral, pharmacological, and neural basis of decision-making
– acute and chronic effects of drugs of abuse (stimulants, cannabinoids, opioids) on cognition and motivation
– neural mechanisms of age-related cognitive decline
Publications
Academic Articles
2024
Cannabis smoke and oral Δ9THC enhance working memory in aged but not young adult subjects.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2024.09.26.615028.
[PMID] 39574655.
2024
Cilia loss on distinct neuron populations differentially alters cocaine-induced locomotion and reward
Journal of Psychopharmacology.
38(2):200-212
[DOI] 10.1177/02698811231219058.
[PMID] 38151883.
2024
Effects of Cohabitation on Neurodevelopmental Outcomes in Rats Discordant for Neonatal Exposure to Sevoflurane.
Biological psychiatry global open science.
4(6)
[DOI] 10.1016/j.bpsgos.2024.100359.
[PMID] 39282654.
2024
Effects of reproductive experience on cost-benefit decision making in female rats.
Frontiers in behavioral neuroscience.
18
[DOI] 10.3389/fnbeh.2024.1304408.
[PMID] 38352625.
2024
Effects of systemic oxytocin receptor activation and blockade on risky decision making in female and male rats.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2024.05.13.593981.
[PMID] 38798601.
2024
Enhanced cognitive flexibility and phasic striatal dopamine dynamics in a mouse model of low striatal tonic dopamine
Neuropsychopharmacology.
49(10):1600-1608
[DOI] 10.1038/s41386-024-01868-5.
[PMID] 38698264.
2024
Neurobehavioral Abnormalities in Offspring of Young Adult Male Rats With a History of Traumatic Brain Injury.
Journal of neurotrauma.
41(7-8):969-984
[DOI] 10.1089/neu.2023.0364.
[PMID] 38279844.
2024
Pictures at an exhibition: A commentary on Benn & Robinson (2024).
Cognitive, affective & behavioral neuroscience.
24(2):368-369
[DOI] 10.3758/s13415-024-01174-z.
[PMID] 38472614.
2024
Risk of Suicidal Ideation and Behavior Following Early‐Onset Idiopathic Restless Legs Syndrome Treatment
Pharmacoepidemiology and Drug Safety.
33(8)
[DOI] 10.1002/pds.5852.
[PMID] 39099262.
2024
Sequencing hour-level temporal patterns of polysubstance use among persons who use cocaine, alcohol, and cannabis: A back-translational approach.
Drug and alcohol dependence.
258
[DOI] 10.1016/j.drugalcdep.2024.111272.
[PMID] 38555662.
2023
Age-Related Changes in Risky Decision Making and Associated Neural Circuitry in a Rat Model
eneuro.
10(1):ENEURO.0385-22.2022
[DOI] 10.1523/eneuro.0385-22.2022.
2023
An ethogram analysis of cutaneous thermal pain sensitivity and oxycodone reward-related behaviors in rats.
Research square.
[DOI] 10.21203/rs.3.rs-2679319/v1.
[PMID] 36993634.
2023
An ethogram analysis of cutaneous thermal pain sensitivity and oxycodone reward-related behaviors in rats.
Scientific reports.
13(1)
[DOI] 10.1038/s41598-023-36729-6.
[PMID] 37380739.
2023
Circuit and Cell-Specific Contributions to Decision Making Involving Risk of Explicit Punishment in Male and Female Rats
The Journal of Neuroscience.
43(26):4837-4855
[DOI] 10.1523/jneurosci.0276-23.2023.
2023
Circuit and cell-specific contributions to decision making involving risk of explicit punishment in male and female rats.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2023.01.15.524142.
[PMID] 36711946.
2023
Cohabitation of Neonatally Sevoflurane-exposed and -unexposed Male Rats Affects Their Respective Behavioral Phenotypes: Research Letter.
Anesthesiology.
138(6):658-661
[DOI] 10.1097/ALN.0000000000004546.
[PMID] 37017655.
2023
Effects of fentanyl self-administration on risk-taking behavior in male rats.
Psychopharmacology.
240(12):2529-2544
[DOI] 10.1007/s00213-023-06447-y.
[PMID] 37612455.
2023
Incident mental health episodes after initiation of gabapentinoids vs. dopamine agonists for early-onset idiopathic restless legs syndrome.
Psychiatry research.
328
[DOI] 10.1016/j.psychres.2023.115479.
[PMID] 37708806.
2023
Intergenerational Perioperative Neurocognitive Disorder in Young Adult Male Rats with Traumatic Brain Injury.
Anesthesiology.
138(4):388-402
[DOI] 10.1097/ALN.0000000000004496.
[PMID] 36637480.
2023
Introduction to special issue on amygdala and value-based decision making.
Behavioural brain research.
437
[DOI] 10.1016/j.bbr.2022.114147.
[PMID] 36209945.
2023
Pharmacokinetics of delta-9-tetrahydrocannabinol following acute cannabis smoke exposure in mice; effects of sex, age, and strain.
Frontiers in pharmacology.
14
[DOI] 10.3389/fphar.2023.1227220.
[PMID] 37701025.
2022
Chronic cocaine causes age-dependent increases in risky choice in both males and females.
Behavioral Neuroscience.
136(3):243-263
[DOI] 10.1037/bne0000509.
[PMID] 35298207.
2022
Dexmedetomidine Diminishes, but Does Not Prevent, Developmental Effects of Sevoflurane in Neonatal Rats.
Anesthesia and analgesia.
135(4):877-887
[DOI] 10.1213/ANE.0000000000006125.
[PMID] 35759382.
2022
GABAB receptors in prelimbic cortex and basolateral amygdala differentially influence intertemporal decision making and decline with age.
Neuropharmacology.
209
[DOI] 10.1016/j.neuropharm.2022.109001.
[PMID] 35189132.
2022
Oxycodone decreases anxiety-like behavior in the elevated plus-maze test in male and female rats.
Behavioural pharmacology.
33(6):418-426
[DOI] 10.1097/FBP.0000000000000690.
[PMID] 35947068.
2022
Test‐retest reliability of a new assessment to detect detailed temporal patterns of polysubstance use
International Journal of Methods in Psychiatric Research.
31(3)
[DOI] 10.1002/mpr.1912.
[PMID] 35684977.
2022
Treatment initiation and utilization patterns of pharmacotherapies for early-onset idiopathic restless legs syndrome
Sleep Medicine.
96:70-78
[DOI] 10.1016/j.sleep.2022.05.003.
[PMID] 35605349.
2021
Acute vagus nerve stimulation enhances reversal learning in rats.
Neurobiology of learning and memory.
184
[DOI] 10.1016/j.nlm.2021.107498.
[PMID] 34332068.
2021
Cocaine and Marijuana Polysubstance Use and Cocaine Use Disorder: Investigating Mediated Effects through Patterns of Cocaine Use.
Journal of dual diagnosis.
17(1):23-33
[DOI] 10.1080/15504263.2020.1849887.
[PMID] 33300839.
2021
Effects of a high-fat diet on impulsive choice in rats.
Physiology & behavior.
229
[DOI] 10.1016/j.physbeh.2020.113260.
[PMID] 33227243.
2021
Effects of repeated adolescent exposure to cannabis smoke on cognitive outcomes in adulthood
Journal of Psychopharmacology.
35(7):848-863
[DOI] 10.1177/0269881120965931.
[PMID] 33295231.
2021
Neuron-specific cilia loss differentially alters locomotor responses to amphetamine in mice.
Journal of neuroscience research.
99(3):827-842
[DOI] 10.1002/jnr.24755.
[PMID] 33175436.
2021
Regulation of risky decision making by gonadal hormones in males and females
Neuropsychopharmacology.
46(3):603-613
[DOI] 10.1038/s41386-020-00827-0.
[PMID] 32919406.
2020
Author response: Testicular hormones mediate robust sex differences in impulsive choice in rats
.
[DOI] 10.7554/elife.58604.sa2.
2020
Distinct relationships between risky decision making and cocaine self-administration under short- and long-access conditions.
Progress in neuro-psychopharmacology & biological psychiatry.
98
[DOI] 10.1016/j.pnpbp.2019.109791.
[PMID] 31676462.
2020
Testicular hormones mediate robust sex differences in impulsive choice in rats
eLife.
9
[DOI] 10.7554/elife.58604.
2020
Using rodent models to understand interactions between gambling and substance use.
Current opinion in behavioral sciences.
31:37-41
[DOI] 10.1016/j.cobeha.2019.10.012.
[PMID] 33102640.
2019
Author response: Optogenetic dissection of basolateral amygdala contributions to intertemporal choice in young and aged rats
.
[DOI] 10.7554/elife.46174.024.
2019
Deconstructing value-based decision making via temporally selective manipulation of neural activity: Insights from rodent models.
Cognitive, affective & behavioral neuroscience.
19(3):459-476
[DOI] 10.3758/s13415-018-00649-0.
[PMID] 30341621.
2019
Effects in rats of adolescent exposure to cannabis smoke or THC on emotional behavior and cognitive function in adulthood.
Psychopharmacology.
236(9):2773-2784
[DOI] 10.1007/s00213-019-05255-7.
[PMID] 31044291.
2019
Enhancing effects of acute exposure to cannabis smoke on working memory performance.
Neurobiology of learning and memory.
157:151-162
[DOI] 10.1016/j.nlm.2018.12.001.
[PMID] 30521850.
2019
Intergenerational Effects of Sevoflurane in Young Adult Rats.
Anesthesiology.
131(5):1092-1109
[DOI] 10.1097/ALN.0000000000002920.
[PMID] 31517640.
2019
Optogenetic dissection of basolateral amygdala contributions to intertemporal choice in young and aged rats
eLife.
8
[DOI] 10.7554/elife.46174.
2019
Pharmacokinetic and Pharmacodynamic Characterization of Tetrahydrocannabinol-Induced Cannabinoid Dependence After Chronic Passive Cannabis Smoke Exposure in Rats.
Cannabis and cannabinoid research.
4(4):240-254
[DOI] 10.1089/can.2019.0049.
[PMID] 32042924.
2019
Recent Updates in Modeling Risky Decision Making in Rodents.
Methods in molecular biology (Clifton, N.J.).
2011:79-92
[DOI] 10.1007/978-1-4939-9554-7_5.
[PMID] 31273694.
2019
Risky decision-making is associated with impulsive action and sensitivity to first-time nicotine exposure.
Behavioural brain research.
359:579-588
[DOI] 10.1016/j.bbr.2018.10.008.
[PMID] 30296531.
2019
The perirhinal cortex supports spatial intertemporal choice stability.
Neurobiology of learning and memory.
162:36-46
[DOI] 10.1016/j.nlm.2019.05.002.
[PMID] 31125611.
2018
Age-Related Declines in Prefrontal Cortical Expression of Metabotropic Glutamate Receptors that Support Working Memory.
eNeuro.
5(3)
[DOI] 10.1523/ENEURO.0164-18.2018.
[PMID] 29971246.
2018
Contributions of medial prefrontal cortex to decision making involving risk of punishment.
Neuropharmacology.
139:205-216
[DOI] 10.1016/j.neuropharm.2018.07.018.
[PMID] 30009836.
2018
Effects of combined brief etomidate anesthesia and postnatal stress on amygdala expression of Cl- cotransporters and corticotropin-releasing hormone and alcohol intake in adult rats.
Neuroscience letters.
685:83-89
[DOI] 10.1016/j.neulet.2018.08.019.
[PMID] 30125644.
2018
Functional Connectivity of Chronic Cocaine Use Reveals Progressive Neuroadaptations in Neocortical, Striatal, and Limbic Networks.
eNeuro.
5(4)
[DOI] 10.1523/ENEURO.0081-18.2018.
[PMID] 30073194.
2018
Functional connectivity, behavioral and dopaminergic alterations 24 hours following acute exposure to synthetic bath salt drug methylenedioxypyrovalerone.
Neuropharmacology.
137:178-193
[DOI] 10.1016/j.neuropharm.2018.04.031.
[PMID] 29729891.
2018
MeCP2 Expression in a Rat Model of Risky Decision Making.
Neuroscience.
369:212-221
[DOI] 10.1016/j.neuroscience.2017.11.016.
[PMID] 29155278.
2018
Monoaminergic modulation of decision-making under risk of punishment in a rat model.
Behavioural pharmacology.
29(8):745-761
[DOI] 10.1097/FBP.0000000000000448.
[PMID] 30394882.
2018
Simultaneous quantification of cannabinoids tetrahydrocannabinol, cannabidiol and CB1 receptor antagonist in rat plasma: An application to characterize pharmacokinetics after passive cannabis smoke inhalation and co-administration of rimonabant.
Journal of pharmaceutical and biomedical analysis.
160:119-125
[DOI] 10.1016/j.jpba.2018.07.004.
[PMID] 30077950.
2018
Stress-induced corticosterone secretion covaries with working memory in aging.
Neurobiology of aging.
71:156-160
[DOI] 10.1016/j.neurobiolaging.2018.07.015.
[PMID] 30144648.
2018
The importance of considering polysubstance use: lessons from cocaine research.
Drug and alcohol dependence.
192:16-28
[DOI] 10.1016/j.drugalcdep.2018.07.025.
[PMID] 30195242.
2017
Adolescent Cannabinoid Use and Cognition; Unexpected Results from a Rat Model of Cannabinoid Self-Administration.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
42(5):983-984
[DOI] 10.1038/npp.2016.212.
[PMID] 27654216.
2017
Cocaine and intertemporal decision making.
.
375-382
2017
Decline of prefrontal cortical-mediated executive functions but attenuated delay discounting in aged Fischer 344 × brown Norway hybrid rats.
Neurobiology of aging.
60:141-152
[DOI] 10.1016/j.neurobiolaging.2017.08.025.
[PMID] 28946018.
2017
Effects of nucleus accumbens amphetamine administration on performance in a delay discounting task.
Behavioural brain research.
321:130-136
[DOI] 10.1016/j.bbr.2017.01.001.
[PMID] 28057530.
2017
Interaction between age and perceptual similarity in olfactory discrimination learning in F344 rats: relationships with spatial learning.
Neurobiology of aging.
53:122-137
[DOI] 10.1016/j.neurobiolaging.2017.01.023.
[PMID] 28259065.
2017
Optogenetic Inhibition Reveals Distinct Roles for Basolateral Amygdala Activity at Discrete Time Points during Risky Decision Making.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
37(48):11537-11548
[DOI] 10.1523/JNEUROSCI.2344-17.2017.
[PMID] 29079687.
2017
Prefrontal cortical GABAergic signaling and impaired behavioral flexibility in aged F344 rats.
Neuroscience.
345:274-286
[DOI] 10.1016/j.neuroscience.2016.02.014.
[PMID] 26873002.
2017
Sex differences in animal models of decision making.
Journal of neuroscience research.
95(1-2):260-269
[DOI] 10.1002/jnr.23810.
[PMID] 27870448.
2016
Behavioral and transcriptomic profiling of mice null for Lphn3, a gene implicated in ADHD and addiction.
Molecular genetics & genomic medicine.
4(3):322-43
[DOI] 10.1002/mgg3.207.
[PMID] 27247960.
2016
Behavioral Characterization of the Effects of Cannabis Smoke and Anandamide in Rats.
PloS one.
11(4)
[DOI] 10.1371/journal.pone.0153327.
[PMID] 27065006.
2016
Deficits in hippocampal-dependent transfer generalization learning accompany synaptic dysfunction in a mouse model of amyloidosis.
Hippocampus.
26(4):455-71
[DOI] 10.1002/hipo.22535.
[PMID] 26418152.
2016
Effects of acute administration of the GABA(B) receptor agonist baclofen on behavioral flexibility in rats.
Psychopharmacology.
233(14):2787-97
[DOI] 10.1007/s00213-016-4321-y.
[PMID] 27256354.
2016
NR2A-Containing NMDARs in the Prefrontal Cortex Are Required for Working Memory and Associated with Age-Related Cognitive Decline.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
36(50):12537-12548
[PMID] 27807032.
2016
Sex differences in a rat model of risky decision making.
Behavioral neuroscience.
130(1):50-61
[DOI] 10.1037/bne0000111.
[PMID] 26653713.
2016
The Psychoactive Designer Drug and Bath Salt Constituent MDPV Causes Widespread Disruption of Brain Functional Connectivity.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
41(9):2352-65
[DOI] 10.1038/npp.2016.40.
[PMID] 26997298.
2015
Affective and cognitive mechanisms of risky decision making.
Neurobiology of learning and memory.
117:60-70
[DOI] 10.1016/j.nlm.2014.03.002.
[PMID] 24642448.
2015
Characterizing olfactory binary mixture interactions in Fischer 344 rats using behavioral reaction times.
Chemical senses.
40(5):325-34
[DOI] 10.1093/chemse/bjv014.
[PMID] 25877697.
2015
Choice impulsivity: Definitions, measurement issues, and clinical implications.
Personality disorders.
6(2):182-98
[DOI] 10.1037/per0000099.
[PMID] 25867841.
2015
Dissociable roles for the basolateral amygdala and orbitofrontal cortex in decision-making under risk of punishment.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
35(4):1368-79
[DOI] 10.1523/JNEUROSCI.3586-14.2015.
[PMID] 25632115.
2015
Modeling Cost–Benefit Decision Making in Aged Rodents
Aging and Decision Making.
17-40
[DOI] 10.1016/B978-0-12-417148-0.00002-9.
2015
Neural mechanisms regulating different forms of risk-related decision-making: Insights from animal models.
Neuroscience and biobehavioral reviews.
58:147-67
[DOI] 10.1016/j.neubiorev.2015.04.009.
[PMID] 26072028.
2014
Adolescent risk taking, cocaine self-administration, and striatal dopamine signaling.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
39(4):955-62
[DOI] 10.1038/npp.2013.295.
[PMID] 24145852.
2014
Adolescent risk taking, cocaine self-administration, and striatal dopamine signaling.
.
39(4)
2014
Behavioral Alterations and Dependence Following Acute and Chronic Exposure To Cannabis Smoke
Neuropsychopharmacology.
39(1):S599-S600
2014
Characterizing olfactory perceptual similarity using carbon chain discrimination in Fischer 344 rats.
Chemical senses.
39(4):323-31
[DOI] 10.1093/chemse/bju001.
[PMID] 24488965.
2014
Characterizing olfactory perceptual similarity using carbon chain discrimination in Fischer 344 rats.
Chemical Senses.
39(4)
2014
Food consumption and weight gain after cessation of chronic amphetamine administration.
Appetite.
78:76-80
[DOI] 10.1016/j.appet.2014.03.013.
[PMID] 24667154.
2014
Food consumption and weight gain after cessation of chronic amphetamine administration.
Appetite.
78:76-80
2014
Impulsivity, risk-taking, and distractibility in rats exhibiting robust conditioned orienting behaviors.
Journal of the experimental analysis of behavior.
102(2):162-78
[DOI] 10.1002/jeab.104.
[PMID] 25130520.
2014
Intake-dependent effects of cocaine self-administration on impulsive choice in a delay discounting task.
Behavioral neuroscience.
128(4):419-29
[DOI] 10.1037/a0036742.
[PMID] 24841739.
2014
Lesions of the Orbitofrontal Cortex Reduce Risk-Taking in Rats
Neuropsychopharmacology.
39(1)
2014
Prefrontal cortical GABAergic dysfunction contributes to age-related working memory impairment.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
34(10):3457-66
[DOI] 10.1523/JNEUROSCI.5192-13.2014.
[PMID] 24599447.
2014
Subtypes of Prefrontal Cortical Nmda Receptors in Working Memory and Normal Aging
Neuropsychopharmacology.
39(1)
2013
Adolescent Risk Taking, Dopamine, and Cocaine: a Vicious Cycle
Biological Psychiatry.
73:40S-41S
2013
Alpha 4 Beta 2{*}and Alpha 7 Nicotinic Acetylcholine Receptor Binding Predicts Choice Preference in Two Cost Benefit Decision-Making Tasks
Neuroscience.
230:121-131
[DOI] 10.1016/j.neuroscience.2012.10.067.
[PMID] 23159316.
2013
Distinct manifestations of executive dysfunction in aged rats.
Neurobiology of aging.
34(9):2164-74
[DOI] 10.1016/j.neurobiolaging.2013.03.019.
[PMID] 23601673.
2013
Effects of ventral striatal lesions on first- and second-order appetitive conditioning.
The European journal of neuroscience.
38(4):2589-99
[DOI] 10.1111/ejn.12255.
[PMID] 23691939.
2013
Prefrontal cortical-striatal dopamine receptor mRNA expression predicts distinct forms of impulsivity.
The European journal of neuroscience.
37(11):1779-88
[DOI] 10.1111/ejn.12191.
[PMID] 23510331.
2012
Altered spatial learning and delay discounting in a rat model of human third trimester binge ethanol exposure.
Behavioural pharmacology.
23(1):54-65
[DOI] 10.1097/FBP.0b013e32834eb07d.
[PMID] 22129556.
2012
Effects of acute administration of nicotinic and muscarinic cholinergic agonists and antagonists on performance in different cost-benefit decision making tasks in rats.
Psychopharmacology.
224(4):489-99
[DOI] 10.1007/s00213-012-2777-y.
[PMID] 22760484.
2012
Effects of developmental nicotine exposure in rats on decision-making in adulthood.
Behavioural pharmacology.
23(1):34-42
[DOI] 10.1097/FBP.0b013e32834eb04a.
[PMID] 22123182.
2012
Initial characterization of mice null for Lphn3, a gene implicated in ADHD and addiction.
Brain research.
1463:85-92
[DOI] 10.1016/j.brainres.2012.04.053.
[PMID] 22575564.
2012
Modeling risky decision making in rodents.
Methods in molecular biology (Clifton, N.J.).
829:165-75
[DOI] 10.1007/978-1-61779-458-2_10.
[PMID] 22231813.
2012
Risk, reward, and decision-making in a rodent model of cognitive aging
Frontiers in Neuroscience.
2011
Dopaminergic modulation of risky decision-making.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
31(48):17460-70
[DOI] 10.1523/JNEUROSCI.3772-11.2011.
[PMID] 22131407.
2011
Effects of acute administration of nicotine, amphetamine, diazepam, morphine, and ethanol on risky decision-making in rats.
Psychopharmacology.
218(4):703-12
[DOI] 10.1007/s00213-011-2363-8.
[PMID] 21638222.
2011
Risk, reward, and decision-making in a rodent model of cognitive aging.
Frontiers in neuroscience.
5
[DOI] 10.3389/fnins.2011.00144.
[PMID] 22319463.
2010
Good things come to those who wait: attenuated discounting of delayed rewards in aged Fischer 344 rats.
Neurobiology of aging.
31(5):853-62
[DOI] 10.1016/j.neurobiolaging.2008.06.004.
[PMID] 18657883.
2010
Self-administered cocaine causes long-lasting increases in impulsive choice in a delay discounting task.
Behavioral neuroscience.
124(4):470-7
[DOI] 10.1037/a0020458.
[PMID] 20695646.
2009
An animal model of hypnotic pain attenuation.
Behavioural brain research.
197(1):198-204
[DOI] 10.1016/j.bbr.2008.08.020.
[PMID] 18793674.
2009
Balancing risk and reward: a rat model of risky decision making.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
34(10):2208-17
[DOI] 10.1038/npp.2009.48.
[PMID] 19440192.
2009
Cocaine self-administration alters the relative effectiveness of multiple memory systems during extinction.
Learning & memory (Cold Spring Harbor, N.Y.).
16(5):296-9
[DOI] 10.1101/lm.1253409.
[PMID] 19389915.
2009
Effects of chronic administration of drugs of abuse on impulsive choice (delay discounting) in animal models.
Behavioural pharmacology.
20(5-6):380-9
[DOI] 10.1097/FBP.0b013e3283305eb4.
[PMID] 19667970.
2009
Effects of prior amphetamine exposure on approach strategy in appetitive Pavlovian conditioning in rats
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202(4)
2009
Effects of prior amphetamine exposure on approach strategy in appetitive Pavlovian conditioning in rats.
Psychopharmacology.
202(4):699-709
[DOI] 10.1007/s00213-008-1353-y.
[PMID] 18850090.
2009
Georges ungar and memory transfer
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181-192
2009
Georges ungar and memory transfer
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181-192
2009
Long-lasting sensitization of reward-directed behavior by amphetamine.
Behavioural brain research.
201(1):74-9
[DOI] 10.1016/j.bbr.2009.01.034.
[PMID] 19428619.
2009
Multiple memory systems and extinction: oral cocaine use selectively impairs “cognitive” latent extinction.
Learning & Memory.
16
2009
Spatial reference and working memory across the lifespan of male Fischer 344 rats
Neurobiology of Aging.
30(4)
2008
Long-term effects of prior cocaine exposure on Morris water maze performance.
Neurobiology of learning and memory.
89(2):185-91
[PMID] 17904876.
2008
Sensory recognition versus motor output: dual components in Pavlovian conditioning.
Experimental Brain Research.
185
2008
Timing in the absence of supraspinal input I: variable, but not fixed, spaced stimulation of the sciatic nerve undermines spinally-mediated instrumental learning.
Neuroscience.
155(4):1030-47
[DOI] 10.1016/j.neuroscience.2008.07.003.
[PMID] 18674601.
2008
Undoing cocaine’s consequences on behavior and brain.
Proceedings of the National Academy of Sciences of the United States of America.
105(44):16829-30
[DOI] 10.1073/pnas.0809529105.
[PMID] 18974216.
2007
Cocaine exposure causes long-term increases in impulsive choice.
Behavioral neuroscience.
121(3):543-9
[PMID] 17592945.
2007
Cognitive impairments in Morris water maze and odor discrimination learning in a subset of aged Fisher 344 rats.
Neurobiology of Aging.
28
2007
Deficits across multiple cognitive domains in a subset of aged Fischer 344 rats.
Neurobiology of aging.
28(6):928-36
[PMID] 16806587.
2006
Encoding changes in orbitofrontal cortex in reversal-impaired aged rats.
Journal of neurophysiology.
95(3):1509-17
[PMID] 16338994.
2006
Post-training amphetamine administration enhances memory consolidation in appetitive Pavlovian conditioning: Implications for drug addiction.
Neurobiology of learning and memory.
86(3):305-10
[PMID] 16750404.
2005
Cocaine makes actions insensitive to outcomes but not extinction: implications for altered orbitofrontal-amygdalar function.
Cerebral cortex (New York, N.Y. : 1991).
15(8):1162-9
[PMID] 15563719.
2005
Memory-influencing intra-basolateral amygdala drug infusions modulate expression of Arc protein in the hippocampus.
Proceedings of the National Academy of Sciences of the United States of America.
102(30):10718-23
[PMID] 16020527.
2004
Cocaine-experienced rats exhibit learning deficits in a task sensitive to orbitofrontal cortex lesions.
The European journal of neuroscience.
19(7):1997-2002
[PMID] 15078575.
2003
A systems approach to orbitofrontal cortex function: recordings in rat orbitofrontal cortex reveal interactions with different learning systems.
Behavioural brain research.
146(1-2):19-29
[PMID] 14643456.
2003
Different roles for orbitofrontal cortex and basolateral amygdala in a reinforcer devaluation task.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
23(35):11078-84
[PMID] 14657165.
2003
Encoding predicted outcome and acquired value in orbitofrontal cortex during cue sampling depends upon input from basolateral amygdala.
Neuron.
39(5):855-67
[PMID] 12948451.
2003
Lesions of nucleus accumbens disrupt learning about aversive outcomes.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
23(30):9833-41
[PMID] 14586012.
2003
Lesions of orbitofrontal cortex and basolateral amygdala complex disrupt acquisition of odor-guided discriminations and reversals.
Learning & memory (Cold Spring Harbor, N.Y.).
10(2):129-40
[PMID] 12663751.
2003
Neural encoding in ventral striatum during olfactory discrimination learning.
Neuron.
38(4):625-36
[PMID] 12765613.
2002
Amygdalo-hypothalamic circuit allows learned cues to override satiety and promote eating.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
22(19):8748-53
[PMID] 12351750.
2002
Disconnection of the basolateral amygdala complex and nucleus accumbens impairs appetitive pavlovian second-order conditioned responses.
Behavioral neuroscience.
116(2):267-75
[PMID] 11996312.
2002
Orbitofrontal lesions in rats impair reversal but not acquisition of go, no-go odor discriminations.
Neuroreport.
13(6):885-90
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[PMID] 11997707.
2002
The basolateral complex of the amygdala is necessary for acquisition but not expression of CS motivational value in appetitive Pavlovian second-order conditioning.
The European journal of neuroscience.
15(11):1841-53
[PMID] 12081664.
2001
A novel method for detecting licking behavior during recording of electrophysiological signals from the brain.
Journal of neuroscience methods.
106(2):139-46
[PMID] 11325433.
2001
Basolateral amygdala-nucleus accumbens interactions in mediating glucocorticoid enhancement of memory consolidation.
The Journal of Neuroscience.
21(7)
2001
Experience-dependent gene expression in the rat hippocampus after spatial learning: a comparison of the immediate-early genes Arc, c-fos, and zif268.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
21(14):5089-98
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2001
Integrating orbitofrontal cortex into prefrontal theory: common processing themes across species and subdivisions.
Learning & memory (Cold Spring Harbor, N.Y.).
8(3):134-47
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2000
D2 Dopamine Receptor Blockade Immediately Post-training Enhances Retention in Hidden and Visible Platform Versions of the Water Maze
Learning & Memory.
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Impaired memory consolidation in rats produced with beta-adrenergic blockade.
Neurobiology of learning and memory.
74(3):259-66
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2000
Involvement of a basolateral amygdala complex-nucleus accumbens pathway in glucocorticoid-induced modulation of memory consolidation.
The European journal of neuroscience.
12(1):367-75
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2000
The basolateral amygdala complex is involved with, but is not necessary for, rapid acquisition of Pavlovian ‘fear conditioning’.
The European journal of neuroscience.
12(8):3044-50
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1999
Differential effects of immediate posttraining sulphide microinfusions into the nucleus accumbens shell and core on Morris water maze retention
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27(2)
1999
Involvement of the posteroventral caudate-putamen in memory consolidation in the Morris water maze.
Neurobiology of learning and memory.
71(2):240-7
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Sulpiride infused into the nucleus accumbens posttraining impairs memory of spatial water maze training.
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Multiple memory systems and cortico-striatal anatomy: A new approach
.
13(2)
Grants
May 2024
ACTIVE
Mechanisms and therapeutic potential of vagus nerve stimulation in aging and Alzheimer's disease
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Jul 2023
ACTIVE
Evaluating the potential of neural oscillation biomarkers in a rodent model of intervention outcome variation: Toward personalized mental health care
Role: Principal Investigator
Funding: DARTMOUTH-HITCHCOCK MEMORIAL CNTR
via NATL INST OF HLTH NIMH
Jun 2023
ACTIVE
Patterns and neurocognitive consequences of opioid-alcohol polysubstance use
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDA
Apr 2023
ACTIVE
Cholinergic Mechanisms in Lewy Body Dementia
Role: Co-Investigator
Funding: NATL INST OF HLTH NINDS
Mar 2023
ACTIVE
Role of cortical catecholamines in regulating motivated behavior and striatal dopamine
Role: Co-Investigator
Funding: NATL INST OF HLTH NIMH
Sep 2022
ACTIVE
Mechanisms and blood-based biomarkers of intergenerational neurobehavioral effects of general anesthetics
Role: Co-Investigator
Funding: NATL INST OF HLTH NICHD
Feb 2022
ACTIVE
Role of Dopamine receptor-expressing cortical projection circuits in cognitive flexibility
Role: Co-Investigator
Funding: NATL INST OF HLTH NIMH
Sep 2021
ACTIVE
Preclinical Assays of Hippocampal-Prefrontal Cortical?Circuit Engagement for Application in Therapeutic Development
Role: Co-Investigator
Funding: NATL INST OF HLTH NIMH
Aug 2021
ACTIVE
Effects of cannabis on age-related cognitive decline and Alzheimers disease pathology
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Jul 2021
– Jul 2021
Optogenetic Modulation of Mesocorticolimbic Brain Networks as a Treatment for Parkinsons Disease Cognitive Dysfunction
Role: Other
Funding: AMER ACAD OF NEUROLOGY
May 2021
– Feb 2023
Effects of cannabis on Alzheimers disease-related pathology and cognitive decline
Role: Principal Investigator
Funding: FL DEPT OF HLTH ED ETHEL MOORE ALZHEIMER
May 2021
ACTIVE
Cognitive and Affective Network Dysfunction and Neuromodulation in Aging and Synucleinopathy
Role: Other
Funding: NATL INST OF HLTH NIA
May 2021
– Apr 2024
Mechanisms and therapeutic potential of vagus nerve stimulation in aging and Alzheimers disease
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Sep 2020
ACTIVE
Opioid and cannabinoid interactions in pain and reward
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDA
Sep 2020
ACTIVE
Identifying patterns of human polysubstance use to guide development of rodent models
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDA
Sep 2020
– Aug 2022
Mechanisms of neurodevelopmental effects of parental exposure to commonly used general anesthetic agents
Role: Co-Investigator
Funding: NATL INST OF HLTH NICHD
Jan 2020
– Jun 2021
Modulation of Synuclein Pathology Through Induction of Gamma Band Oscillations in a Mouse Model of DLB
Role: Other
Funding: UF FOUNDATION
Jul 2019
– Jun 2022
Novel neuromodulation of motivated and addictive behaviors
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDA
Jun 2019
– May 2022
Opioid and cannabinoid interactions in pain and reward
Role: Co-Investigator
Funding: UF RESEARCH
Jun 2019
– May 2021
DRPD-ROF2019: A Microfluidics Optrode: A Next Generation Approach to Brain Network Modulation in Parkinsons Disease
Role: Principal Investigator
Funding: UF RESEARCH
Sep 2018
– Aug 2020
Identifying patterns of human polysubstance use to guidedevelopment of rodent models
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDA
Sep 2018
– Aug 2023
Decision making and basolateral amygdala dysfunction in aging
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Apr 2018
– Aug 2020
Hippocampal and dopaminergic?mechanisms of novelty detection underlying cognitive resilience in aging
Role: Other
Funding: NATL INST OF HLTH NIA
Sep 2017
– Aug 2021
Critical Mechanisms Underlying THC Neurotoxicity in Developing CNS
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDA
May 2017
– Jul 2019
Neural circuits and mechanisms underlying maladaptive risk-taking following cocaine self-administration
Role: Other
Funding: NATL INST OF HLTH NIDA
Jan 2017
– Mar 2021
Cognitive Augmentation through Neuroplasticity (CAN)
Role: Co-Investigator
Funding: US DEPT OF DEFENSE ADV RES PROJ AGCY
Jun 2016
– May 2018
Dissecting interneuron function in addiction using optogenetics
Role: Principal Investigator
Funding: UF DSR OPPORTUNITY FUND
Sep 2015
– Aug 2020
Role of the limbic-hypothalamic-pituitary-adrenal (LHPA) axis and gamma-aminobutyric acid type A receptor (GABAAR)-mediated excitation in the developmental central and systemic effects of neonatal anesthesia.
Role: Project Manager
Funding: NATL INST OF HLTH NINDS
Jul 2015
– Jun 2018
Lasting behavioral and neuroimaging consequences of adolescent exposure to cannabis smoke
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDA
Apr 2015
– Jan 2021
Risk taking and cocaine use: interactions, mechanisms, and therapeutic targets
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDA
Apr 2015
– Mar 2018
Imaging In Vivo Neural Mechanisms of Synthetic Cathinones (Bath Salts)
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDA
Mar 2015
– Feb 2017
Risk-taking and the nucleus accumbens: neural circultry and the impact of cocaine
Role: Principal Investigator
Funding: UF FOUNDATION
via THOMAS H MAREN FOU
Feb 2015
– Mar 2019
Development of a rat model of cannabis smoke self-administration
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDA
May 2014
– Mar 2020
Neural Mechanisms of Cognitive Decline in Aging
Role: Project Manager
Funding: NATL INST OF HLTH NIA
Education
Fellowship: Psychological and Brain Sciences
1998-2002
·
Johns Hopkins University
PhD, Biological Sciences
1998
·
University of California, Irvine
BA, Psychology
1994
·
Yale University
Contact Details
Phones:
- Business:
- (352) 294-5203
Emails:
- Business:
- setlow@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100256
GAINESVILLE FL 32610 - Business Street:
-
PO Box 100256
GAINESVILLE FL 32610