Committees

Executive Committee

Sara J Nixon

Sara J Nixon Ph.D.

Professor & Co-Vice Chair
Department: MD-PSYCHIATRY
Phone: (352) 294-4920

Dr. Nixon is Professor of Psychiatry and Psychology, Chief of Addiction Research, Director of the Biobehavioral Core of the University of Florida Clinical and Translational Science Institute, and Director of the Neurocognitive Laboratory in the UF Department of Psychiatry. She is an experienced clinical researcher in the area of substance abuse and dependence.

Because of the complex nature of substance abuse, her work uses comprehensive behavioral assessments including neuropsychological testing, brain electrophysiology (electroencephalography and event-related potentials), and clinical research interviews. This work has provided many opportunities for Dr. Nixon to provide training to graduate students and post-doctoral associates.

In addition to neurobehavioral research, Dr. Nixon has sustained a strong interest in community outreach and education. During her tenure in Oklahoma, she was instrumental in the development and implementation of the Oscar A. Parsons Summer Institute which engaged experts from across the country in the provision of education and training programs for community service providers and she was a key component (with Dr. Deborah Jones-Saumty) in the American Indian Research Group of Oklahoma which fostered substance-related research initiatives among the non-reservation residing tribes in the state. Following the Oklahoma City Bombing (1995), she diverted a portion of her efforts to another concern; the psychiatric impact of the tragedy on the community and emergency responders. Her continued commitment to community outreach is reflected in her on-going work focusing on the cognitive, psychological and social concomitants of substance use and her participation in a variety of workshops, seminars, committees and councils.

 

Dr. Nixon has authored over 110 peer-reviewed articles and book chapters as well as edited two books. She has made over 200 scientific presentations and held grants and awards from a variety of private, state and national sources including the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Institute on Drug Abuse (NIDA), the Department of Veterans Affairs (VA), and more. She is completing her tenure as the Immediate Past President of the Research Society on Alcoholism. Within the American Psychological Association, Dr. Nixon is a Fellow in both Divisions 28 (Substance Use and Psychopharmacology) and 50 (Addiction) of the American Psychological Association. She served as the Member-at-large for Division 50 from 2006-2009.

Accomplishments:
  • Presidential Citation for Outstanding Service to APA Division 50
    2019 · Society of Addiction Psychology
  • Henri Begleiter Excellence in Research Award
    2018 · Research Society on Alcoholism
  • University of Florida Term Professorship
    2017-2020 · University of Florida
  • Exemplary Teacher Award
    2017 · University of Florida, College of Medicine
  • University of Florida Research Foundation Professor
    2015-2017 · University of Florida
  • Fellow
    2007 · American Psychological Association
  • Seixas Outstanding Service Award
    2006 · Research Society on Alcoholism
  • Fellow
    2006 · American Psychological Association (Division 50)
  • Arnold and Bess Ungerman Endowed Chair
    2001-2003 · Department of Psychiatry & Behavioral Sciences, University of Oklahoma Health Sciences Center
  • Biological Psychology Graduate Student Classroom Teaching Award
    2001-2002 · University of Oklahoma Health Sciences Center
  • Gordon H. Deckert Award for Sustained Excellence in Departmental Educational Endeavors
    2000 · Department of Psychiatry & Behavioral Sciences, University of Oklahoma Health Sciences Center
  • Provost’s Award for Outstanding Research (Senior Faculty)
    1999 · University of Oklahoma Health Sciences Center
  • Provost's Research Award for Junior Faculty
    1991 · University of Oklahoma Health Sciences Center
Research Summary:

Dr. Nixon uses neurobehavioral methods and models to examine the acute and chronic effects of alcohol and other drugs. Within her clinical research, her team also explores sex differences, the effects of age, and the import of ethnic/racial minority status.

Because of the complex nature of substance abuse, Dr. Nixon’s work uses comprehensive behavioral assessments including neuropsychological testing, brain electrophysiology (electroencephalography and event-related potentials), and clinical research interviews. In addition to neurobehavioral research, Dr. Nixon has sustained a strong interest in community outreach and education. Her continued commitment to community outreach is reflected in her on-going work focusing on the cognitive, psychological and social concomitants of substance use.

Another study in her laboratory includes analysis of a recently completed study funded by the NIAAA exploring the acute effects of alcohol in healthy older (55-70) and younger social drinkers. Although recruitment for this study has concluded, several key issues including the analysis of sex differences and driving performance under different conditions remain to be examined.

In addition to these efforts, her team is involved in the conduct of a pilot study designed to assess the feasibility and efficacy of an FDA approved medication on cognition and abstinence in small group of men and women seeking treatment for alcohol use disorders. In the near future, we anticipate initiating a Phase 2 trial that will examine the impact of a new compound on smoking cessation efforts in a sample of healthy current smokers.

Publications:
Grants:
  • Apr 2020 ACTIVE
    18/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT THE UNIVERSITY OF FLORIDA
    NATL INST OF HLTH NIDA · Principal Investigator
  • Apr 2020 – Mar 2021
    UCSD Sub – ABCD Consortium Coordinating Center – Participants
    UNIV OF CALIFORNIA SAN DIEGO · Principal Investigator
  • Apr 2020 – Mar 2021
    ABCD Consortium Coordinating Center
    UNIV OF CALIFORNIA SAN DIEGO · Principal Investigator
  • Apr 2020 ACTIVE
    National Drug Early Warning System Coordinating Center
    NATL INST OF HLTH NIDA · Co-Investigator
  • Sep 2019 ACTIVE
    Florida Development in Early Childhood: Adversity and Drug Exposure (FL-DECADE) Study
    NATL INST OF HLTH NIDA · Project Manager
  • Jul 2019 ACTIVE
    UF Substance Abuse Training Center in Public Health
    NATL INST OF HLTH NIDA · Co-Investigator
  • Jul 2019 – Jun 2020
    Retrospective Longitudinal Analysis of Hair Cortisol Concentrations among Treatment-seekers with Alcohol Use Disorder: The role of Cognitive Training on Stress Systems
    RESEARCH SOCIETY ON ALCOHOLISM · Other
  • Feb 2019 – Feb 2021
    SoAP Student Research Grant
    AMER PSYCHOLOGICAL ASSO · Principal Investigator
  • Nov 2018 – Mar 2020
    Peripheral Correlates of Cognitive Training
    UF FOU · Principal Investigator
  • Sep 2018 ACTIVE
    Enhancing Recovery Outcomes in Alcohol Use Disorder: Cognitive Training as an Adjunct to Treatment
    NATL INST OF HLTH NIAAA · Other
  • Aug 2018 ACTIVE
    Characterizing the effects of family history of alcoholism on alcohol analgesia
    NATL INST OF HLTH NIAAA · Co-Investigator
  • Aug 2018 – May 2019
    ABCD-USA Consortium: Coordinating Center
    UNIV OF CALIFORNIA SAN DIEGO · Principal Investigator
  • Jun 2018 – Apr 2020
    ABCD-USA Consortium: Research Project
    UNIV OF MICHIGAN ANN ARBOR · Principal Investigator
  • Apr 2017 – Mar 2020
    Sex Differences, Cognitive Training & Emotion Processing: A pilot study of Treatment-Seeking Men and Women with Alcohol Use Disorder
    NATL INST OF HLTH NIAAA · Principal Investigator
  • Jul 2016 – Jul 2019
    Testing a Smartphone Breathalyzer and BAC Estimator in Young Adult Heavy Drinkers
    NATL INST OF HLTH NIAAA · Co-Investigator
  • Sep 2015 – Apr 2020
    9/13 ABCD-USA Consortium: Research Project
    UNIV OF MICHIGAN ANN ARBOR · Principal Investigator
  • Aug 2015 – Jul 2018
    Effects of GTS-21 on smoking behavior and neurocognitive function
    NATL INST OF HLTH NIDA · Principal Investigator
  • Mar 2015 – Apr 2020
    Texas External Quality Review Organization Vendor and Quality Vendor
    STATE OF TEXAS HLTH HUMAN SERV COM · Project Manager
  • Sep 2013 – Aug 2018
    Neurobehavioral & emotional deficits in male & female alcoholics
    NATL INST OF HLTH NIAAA · Principal Investigator
  • Jul 2007 – Aug 2016
    Clinical and Translational Science Institute
    UF RESEARCH FOU · Project Manager
Patents:
  • Issued November 2016
    Quantitative Measure of Home Functionality in Children with Mitochondrial Diseases
    #TXu 1-988-486
  • Issued January 2016
    Therapies to Improve Smoking Cessation in Neuropsychiatric and Depressed Patients
    #9,233,109
Joanna Peris

Joanna Peris Ph.D.

Associate Professor
Department: Pharmacodynamics
Phone: (352) 273-7688

The Peris lab is currently studying the neurochemical mechanisms of ethanol addiction. As part of this research, we measure how dopaminergic and amino acid neurotransmission in brain reward circuitry (e.g., nucleus accumbens, ventral tegmental area) is altered in rodents exhibiting high degrees of ethanol self-administration. We have developed the “jello shot” method of ethanol self-administration with Dr. Neil Rowland of the Department of Psychology. This model results in pharmacologically relevant levels of ethanol intake in non-genetically-selected rodents, but also controls for non-ethanol reward, caloric consumption and comparable levels of operant responding by the use of non-ethanol gelatin as a control reinforcer. Utilizing a combination of behavioral and microdialysis techniques, we have demonstrated that previous binge ethanol exposures selectively increase ethanol intake, ethanol reward and glutamate levels in nucleus accumbens while not affecting plain gel intake or neurotransmission during plain gel reward. Another novel finding indicates the importance of elevations in glycine in the nucleus accumbens during anticipation of reward.

Our most recent work, in collaboration with Dr. Eric G. Krause in our department, has focused on the role of oxytocin in the regulation of reward circuitry and its impact on ethanol intake. We have found that oxytocin receptors are expressed by both dopamine and glutamate neurons in the ventral tegmental area which might mediate oxytocin inhibition of ethanol intake. We are currently developing optogenetic techniques to address how selective activation of neurons in reward centers that express oxytocin receptors is altered by excessive ethanol intake.

Publications:
Grants:
  • Jul 2018 – Jun 2020
    Ethanol dysregulation of oxytocin-mediated reward
    NATL INST OF HLTH NIAAA · Principal Investigator
  • Jul 2015 – Jul 2016
    Oxytocin Receptors in Alcoholism
    UF FOU · Principal Investigator
Education:
  • 1984
    Ph.D.
    Oregon Health Sciences University, School of Medicine
  • 1982
    M.S.
    Oregon Health Sciences University, School of Medicine
  • 1980
    B.S.
    Bowling Green State University
Marieta B Heaton

Marieta B Heaton

Professor
Department: MD-NEUROSCIENCE-GENERAL
Phone: (352) 273-5094
Publications:
Grants:
  • Sep 2017 – Aug 2021
    Critical Mechanisms Underlying THC Neurotoxicity in Developing CNS
    NATL INST OF HLTH NIDA · Principal Investigator
  • Aug 2016 – Jul 2018
    Mechanisms of Choline Mitigation of Ethanol Toxicity in Developing CNS
    NATL INST OF HLTH NIAAA · Principal Investigator
Jeff Boissoneault

Jeff Boissoneault Ph.D.

Assistant Professor And Co-Director, Center For Pain Research And Behavioral Health
Department: Department of Clinical and Health Psychology
Phone: (352) 273-6147
Accomplishments:
  • Provost's Excellence Award for Assistant Professors
    2021 · Office of the Provost – University of Florida
  • Dean's Citation Paper Award
    2020 · College of Public Health and Health Professions – University of Florida
  • Dean’s Citation Paper Award
    2018 · College of Public Health and Health Professions – University of Florida
  • Most Outstanding Research Award
    2017 · Department of Medicine – University of Florida
  • Most Outstanding Research Award
    2016 · Department of Medicine – University of Florida
  • Building Bridges Award
    2015 · National Institute for Dental and Craniofacial Research (NIDCR)
  • Young Investigator Travel Award
    2013 · Research Society on Alcoholism
  • Student Merit Travel Award
    2008-2012 · Research Society on Alcoholism
  • Grinter Fellowship
    2007-2008 · University of Florida College of Medicine
Research Summary:

Dr. Boissoneault’s research focuses on the application of behavioral, psychophysiological, and neuroimaging approaches to the study of a) pain and related constructs (e.g., fatigue); b) alcohol and substance use; and c) their interaction. For instance, he is interested in improving understanding of how pain may influence alcohol effects and use behavior, as well as how alcohol use affects pain processing. He also has a strong interest in mechanisms underlying placebo efficacy, pain-related decision making, and the acute and chronic neurobehavioral effects of alcohol use.

Publications:
Grants:
  • May 2021 ACTIVE
    Impact of Delayed Onset Muscle Soreness on Demand for Alcohol and Marijuana among Co-Users
    NATL INST OF HLTH NIAAA · Other
  • Jul 2020 ACTIVE
    Impact of Delayed Onset Muscle Soreness on Demand for Alcohol and Marijuana among Co-Users
    RESEARCH SOCIETY ON ALCOHOLISM · Other
  • May 2020 ACTIVE
    Mechanisms and Modification of Pain Modulatory Capacity
    NATL INST OF HLTH NIAMS · Co-Investigator
  • May 2019 ACTIVE
    Acute Effects of Alcohol Use on Chronic Orofacial Pain
    NATL INST OF HLTH NIAAA · Principal Investigator
  • Aug 2018 ACTIVE
    Characterizing the effects of family history of alcoholism on alcohol analgesia
    NATL INST OF HLTH NIAAA · Principal Investigator
  • Jul 2017 ACTIVE
    Brain Imaging and Pain: Analysis of Placebo Analgesia
    NATL CTR FOR COMPLEM AND INTEGRATIVE HLT · Co-Investigator
Education:
  • 2012
    Ph.D. (Medical Sciences)
    University of Florida
  • 2007
    B.A. (Biology)
    New College of Florida
Barry Setlow

Barry Setlow Ph.D.

Professor
Department: MD-PSYCHIATRY
Phone: (352) 294-5203

Barry Setlow received his PhD in 1998 from the University of California, Irvine, where he worked with Jim McGaugh on amygdala-striatal systems involved in consolidation of different forms of learning and memory. He went on to post-doctoral training with Michela Gallagher at Johns Hopkins University, where he continued work on the role of amygdala-striatal systems in different forms of learning, using both behavioral and single-unit electrophysiological recording techniques. From there he moved to a position as an assistant professor at Texas A&M University, where his research focussed on the effects of both acute and chronic exposure to drugs of abuse on cognition, with a particular focus on decision-making. Dr. Setlow joined the Department of Psychiatry in 2010, where he is continuing his research on interactions between drug abuse and decision-making, as well as collaborating with other UF investigators on animal models of age-related cognitive decline.

Accomplishments:
  • UF Research Foundation Professorship
    2018-2021 · University of Florida
  • Fellow
    2017-Current · University of California, Irvine Center for the Neurobiology of Learning and Memory
  • UF Term Professorship
    2017-2020 · University of Florida
  • Exemplary Teacher
    2016 · University of Florida, College of Medicine
  • Faculty of Neuroscience Leadership and Service Award
    2010 · Texas A&M University
  • Young Investigator Travel Award
    2008 · American College of Neuropsychopharmacology
  • J. L. McGaugh Award for Excellence in Graduate Research
    1998 · Department of Psychobiology, University of California, Irvine
  • Ralph Waldo Gerard Prize in the History of Neuroscience
    1996 · University of California, Irvine
Research Summary:

Research Interests:

– behavioral, pharmacological, and neural basis of decision-making

– acute and chronic effects of drugs of abuse (stimulants, cannabinoids, opioids) on cognition and motivation

– neural mechanisms of age-related cognitive decline

Publications:
Grants:
  • Jul 2021 – Jul 2021
    Optogenetic Modulation of Mesocorticolimbic Brain Networks as a Treatment for Parkinsons Disease Cognitive Dysfunction
    AMER ACAD OF NEUROLOGY · Other
  • May 2021 ACTIVE
    Mechanisms and therapeutic potential of vagus nerve stimulation in aging and Alzheimers disease
    NATL INST OF HLTH NIA · Principal Investigator
  • May 2021 ACTIVE
    Cognitive and Affective Network Dysfunction and Neuromodulation in Aging and Synucleinopathy
    NATL INST OF HLTH NIA · Other
  • Mar 2021 ACTIVE
    Effects of cannabis on Alzheimers disease-related pathology and cognitive decline
    FL DEPT OF HLTH ED ETHEL MOORE ALZHEIMER · Principal Investigator
  • Sep 2020 ACTIVE
    Opioid and cannabinoid interactions in pain and reward
    NATL INST OF HLTH NIDA · Co-Investigator
  • Sep 2020 ACTIVE
    Identifying patterns of human polysubstance use to guide development of rodent models
    NATL INST OF HLTH NIDA · Co-Investigator
  • Sep 2020 ACTIVE
    Mechanisms of neurodevelopmental effects of parental exposure to commonly used general anesthetic agents
    NATL INST OF HLTH NICHD · Co-Investigator
  • Jan 2020 – Jun 2021
    Modulation of Synuclein Pathology Through Induction of Gamma Band Oscillations in a Mouse Model of DLB
    UF FOU · Other
  • Jul 2019 ACTIVE
    Novel neuromodulation of motivated and addictive behaviors
    NATL INST OF HLTH NIDA · Principal Investigator
  • Jun 2019 ACTIVE
    DRPD-ROF2019: A Microfluidics Optrode: A Next Generation Approach to Brain Network Modulation in Parkinsons Disease
    UF RESEARCH · Principal Investigator
  • Jun 2019 ACTIVE
    Opioid and cannabinoid interactions in pain and reward
    UF RESEARCH · Co-Investigator
  • Sep 2018 – Aug 2020
    Identifying patterns of human polysubstance use to guidedevelopment of rodent models
    NATL INST OF HLTH NIDA · Co-Investigator
  • Sep 2018 ACTIVE
    Decision making and basolateral amygdala dysfunction in aging
    NATL INST OF HLTH NIA · Principal Investigator
  • Apr 2018 – Aug 2020
    Hippocampal and dopaminergic?mechanisms of novelty detection underlying cognitive resilience in aging
    NATL INST OF HLTH NIA · Other
  • Sep 2017 – Aug 2021
    Critical Mechanisms Underlying THC Neurotoxicity in Developing CNS
    NATL INST OF HLTH NIDA · Co-Investigator
  • May 2017 – Jul 2019
    Neural circuits and mechanisms underlying maladaptive risk-taking following cocaine self-administration
    NATL INST OF HLTH NIDA · Other
  • Jan 2017 – Mar 2021
    Cognitive Augmentation through Neuroplasticity (CAN)
    US DEPT OF DEFENSE DARPA · Co-Investigator
  • Jun 2016 – May 2018
    Dissecting interneuron function in addiction using optogenetics
    UF DSR OPPORTUNITY FUND · Principal Investigator
  • Sep 2015 – Aug 2020
    Role of the limbic-hypothalamic-pituitary-adrenal (LHPA) axis and gamma-aminobutyric acid type A receptor (GABAAR)-mediated excitation in the developmental central and systemic effects of neonatal anesthesia.
    NATL INST OF HLTH NINDS · Project Manager
  • Jul 2015 – Jun 2018
    Lasting behavioral and neuroimaging consequences of adolescent exposure to cannabis smoke
    NATL INST OF HLTH NIDA · Principal Investigator
  • Apr 2015 – Jan 2021
    Risk taking and cocaine use: interactions, mechanisms, and therapeutic targets
    NATL INST OF HLTH NIDA · Principal Investigator
  • Apr 2015 – Mar 2018
    Imaging In Vivo Neural Mechanisms of Synthetic Cathinones (Bath Salts)
    NATL INST OF HLTH NIDA · Co-Investigator
  • Mar 2015 – Feb 2017
    Risk-taking and the nucleus accumbens: neural circultry and the impact of cocaine
    UF FOU · Principal Investigator
  • Feb 2015 – Mar 2019
    Development of a rat model of cannabis smoke self-administration
    NATL INST OF HLTH NIDA · Principal Investigator
  • May 2014 – Mar 2020
    Neural Mechanisms of Cognitive Decline in Aging
    NATL INST OF HLTH NIA · Project Manager
Education:
  • 1998-2002
    Fellowship: Psychological and Brain Sciences
    Johns Hopkins University
  • 1998
    PhD, Biological Sciences
    University of California, Irvine
  • 1994
    BA, Psychology
    Yale University
Catherine L Striley

Catherine L Striley PhD, MSW, MPE

Associate Professor
Department: PHHP-COM EPIDEMIOLOGY
Phone: (352) 273-5359

Catherine Woodstock Striley, PhD, MSW, ACSW, MPE received the Master of Social Work in 1989 and the Doctorate of Philosophy in Social Work from the Brown School at Washington University in St. Louis in 2002 where she was a National Institute of Mental Health(NIMH) predoctoral fellow. The National Institute on Drug Addiction (R03) funded her dissertation research. She completed the Master of Science in Epidemiology from the Washington University School of Medicine in 2004 and completed a three-year postdoctoral fellowship in Epidemiology and Biostatistics funded by NIH in the Department of Psychiatry in 2005. She was a faculty member in that department from 2005 to June of 2011. She has been a co-investigator on many community-engaged NIH-funded studies conducted by Dr. Linda Cottler among community members, out-of-treatment drug users and women in the criminal justice system. With regards to research in drug use disorder epidemiology, Dr. Striley just completed revising the Substance Abuse Module for Kratom Use Disorder and conducted a study among 80 people who use kratom and as a co-investigator on the National Drug Early Warning System (NDEWS) is managing the Virtual HealthStreet monitoring of new drug trends in the community. She is also in the field with a randomized trial to test two community health worker interventions to increase LDCT screening for lung cancer among women 50 – 77 years old. Dr. Striley is Deputy Director of HealthStreet, a Community Health Worker (CHW) powered research site. Dr. Striley has been very involved in training in ethical research conduct and accountability. She was funded by the Office of Research Integrity to plan and co-direct the First Biannual Responsible Conduct of Research Education Instruction and Training conference at Washington University and was funded by the ORI to run a regional conference on Mentoring for the Responsible Conduct of Research. She currently teaches Population Health in Medicine, Psychiatric Epidemiology, and Ethics for Population Health and mentors PhD, MSE and MPH students. She is the program director for the Master of Science in Epidemiology and the Certificate in Psychiatric Epidemiology programs.

Accomplishments:
  • PHHP Doctoral Mentor of the Year
    2019 · University of Florida College of Public Health and Health Professions
Certifications:
  • Academy of Certified Social Workers
    National Association of Social Workers
Research Summary:

As a psychiatric epidemiologist, Dr. Striley conducts community-engaged research that aims to increase community members’ recognition of need for health screening, mental health and behavioral health services and to decrease barriers to those services. She has extensive training and experience in community engaged research, including recruitment and retention of diverse community members, and in drug use, abuse and misuse epidemiology. Dr. Striley is one of the few researchers who conducts research in caffeine and energy drink misuse. She is also researching the epidemiology of movement disorders including Tourette Disorder, Dystonia and Essential Tremor.

Publications:
Grants:
  • Jul 2021 ACTIVE
    CDC-RFA-IP21-2113
    CTRS FOR DISEASE CONTROL AND PREVENTION · Co-Investigator
  • Apr 2020 ACTIVE
    National Drug Early Warning System Coordinating Center
    NATL INST OF HLTH NIDA · Co-Investigator
  • Apr 2019 – Apr 2020
    Tremor Reports Among College Undergraduate Students (TRAC-US)
    HOPENET · Principal Investigator
  • Sep 2018 – Aug 2020
    Identifying patterns of human polysubstance use to guidedevelopment of rodent models
    NATL INST OF HLTH NIDA · Co-Investigator
  • Jul 2018 ACTIVE
    ABCD – Social Development Study
    UNIV OF PITTSBURGH · Co-Investigator
  • Mar 2018 – Feb 2021
    Precision Public Health Approaches to Reduce Disparities in Memory Disorder Screening in Rural Minority Communities
    FL DEPT OF HLTH ED ETHEL MOORE ALZHEIMER · Co-Investigator
  • Aug 2017 ACTIVE
    Health outcomes and cognitive effects of marijuana use among persons living with HIV/AIDS
    NATL INST OF HLTH NIDA · Project Manager
  • Feb 2016 – Feb 2019
    Prevalence of TD and tics among a community-recruited sample of adults from Haiti
    TOURETTE ASSOCIATION OF AMERICA · Principal Investigator
  • Feb 2016 – Jan 2018
    Diseases related to alzheimer's disease, 2015-2016
    FL DEPT OF HLTH ED ETHEL MOORE ALZHEIMER · Project Manager
  • Aug 2015 – May 2021
    University of Florida – Mt. Sinai Medical Center AD Research Center
    NATL INST OF HLTH NIA · Co-Investigator
  • Feb 2014 – Oct 2018
    Preventing Hospital Readmissions through CHWs
    UF HEALTH SHANDS HOSPITAL · Principal Investigator
  • Jul 2011 – May 2017
    Transformative Approach To Reduce Research Disparities Towards Drug Abusers
    NATL INST OF HLTH NIDA · Project Manager
  • Jul 2007 – Aug 2016
    Clinical and Translational Science Institute
    UF RESEARCH FOU · Project Manager
Education:
  • 2004
    Master of Psychiatric Epidemiology
    Washington University School of Medicine
  • 2002
    Doctor of Philosophy/Social Work
    Brown School, Washington University in St. Louis
  • 1989
    Master of Social Work
    Brown School, Washington University in St. Louis

Internal/Community Advisory Committee:

Scientific Members:

Regina Bussing

Regina Bussing M.D.

Psychiatry Chair & Professor
Department: MD-PSYCHIATRY
Phone: (352) 294-4914

Dr. Bussing holds the position of Professor and Chair of the Department of Psychiatry at UF, and in 2016 was named the Donald Dizney Professor in recognition of her academic leadership role.

Dr. Bussing received her medical degree from the Justus Liebig University in Giessen, Germany. She subsequently completed her psychiatry residency and child and adolescent fellowship at the University of Florida in Gainesville, as well as a Master of Science degree in health services research from the UCLA School of Public Health.

Dr. Bussing’s research expertise spans mental health services, measure development, pharmaco-epidemiology, psychotherapy intervention, and clinical pharmacology trials research. As NIMH-funded investigator studying, she led studies assessing access and quality of care for attention deficit hyperactivity disorder (ADHD). Dr. Bussing also conducted a double-blind randomized, controlled trial to assess antidepressant medication related activation phenomena in youth with obsessive compulsive disorder (OCD). She was the co-investigator of an NIH funded randomized clinical trial assessing preschoolers’ response to a non-medication intervention for ADHD, Parent Child Interaction Therapy (PCIT). Furthermore, she collaborated on several other pivotal NIH funded children’s mental health services studies and served as principal investigator on multiple pediatric clinical psychopharmacology trials for ADHD, depression, PTSD, panic disorder and Tourette syndrome. More recently, Dr. Bussing collaborated as clinical lead on measure development for the CMS inpatient psychiatric facilities (IPF) quality program, including an IPF-specific readmission measure.

Dr. Bussing has served as reviewer and chair for multiple NIH and CDC study sections and on advisory boards for several organizations, including Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD), PCIT International and the National Alliance on Mental Illness (NAMI).

Accomplishments:
  • UF College of Medicine Term Professor
    2018-2021 · University of Florida
  • Donald R. Dizney Chair in Psychiatry
    2016-Current · University of Florida
  • Labeled Praise Award for significant and sustained contributions to the advancement of Parent-Child Interaction Therapy (PCIT)
    2015 · PCIT International
  • Faculty Enhancement Opportunity Award
    2012 · University of Florida
  • Distinguished Fellow
    2012 · American Academy of Child and Adolescent Psychiatry
  • Distinguished Fellow
    2011 · American Psychiatric Association
  • Distinguished Fellow
    2011 · Florida Psychiatric Society
  • Elaine Schlosser Lewis Award for research on attention-deficit disorder – best 2010 paper published (second author)
    2010 · Journal of the AACAP
  • Elaine Schlosser Lewis Award for research on attention-deficit disorder – best paper published (first author)
    1997 · Journal of the AACAP
Certifications:
  • Child and Adolescent Psychiatry
    American Board of Psychiatry and Neurology
  • Psychiatry
    American Board of Psychiatry and Neurology
Specialties:
  • Psychiatry
Subspecialties:
  • Child and Adolescent Psychiatry
Clinical Interests:
  • Adolescent depression
  • Attention deficit hyperactivity disorder
  • Child neglect and emotional abuse
  • Depression
  • Discussing death with children
  • Generalized anxiety disorder
  • Hyperactivity and children
  • Major depression
  • Reactive attachment disorder of infancy or early childhood
  • Separation anxiety in children
  • Social anxiety disorder
  • Stress in childhood
  • Suicide and suicidal behavior
Publications:
Grants:
  • Oct 2018 ACTIVE
    Florida and Virgin Islands Deaf-Blind Cooperative
    US DEPT OF EDUCATION · Principal Investigator
  • Jan 2018 ACTIVE
    DCF Medication Consult Helpline
    FL DEPT OF CHILDREN AND FAMILIES · Principal Investigator
  • Apr 2017 – Apr 2018
    VA-Gainesville IPA for Drake Morgan – Dr. Wang, PI
    US DEPT OF VET AFF GAINESVILLE MED CTR · Principal Investigator
  • Apr 2017 – Apr 2018
    VA-Gainesville IPA for Zhihui Yang – Dr. Wang, PI
    US DEPT OF VET AFF GAINESVILLE MED CTR · Project Manager
  • Apr 2017 – Apr 2019
    VA-Gainesville IPA for Fan Lin -Dr. Wang, PI
    US DEPT OF VET AFF GAINESVILLE MED CTR · Project Manager
  • Sep 2016 – Sep 2020
    The Child Health Quality (CHeQ) Partnership Program
    AGCY HEALTHCARE RES AND QUALITY · Co-Investigator
  • Jan 2016 – Dec 2017
    DCF Medication Consult Helpline
    FL DEPT OF CHILDREN AND FAMILIES · Principal Investigator
  • Oct 2013 – Sep 2019
    Florida and Virgin Islands Deaf-Blind Cooperative
    US DEPT OF EDUCATION · Principal Investigator
  • Aug 2012 – Mar 2016
    A Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Safety and Efficacy of Fixed-dose Once-daily Oral Aripiprazole in Children and Adolescents with Tourettes Disorder
    OTSUKA AMERICA PHARMACEUTICAL · Principal Investigator
  • May 2012 – May 2017
    SPRITES: SERTRALINE PEDIATRIC REGISTRY FOR THE EVALUATION OF SAFETY
    DUKE UNIVERSITY CLINICAL RES INST · Principal Investigator
  • Jun 2011 – Jun 2017
    A Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Safety and Efficacy of Fixed-dose Once-weekly Oral Aripiprazole in Children and Adolescents with Tourettes Disorder
    LABCORP DRUG DEVELOPMENT · Principal Investigator
Education:
  • 1989
    Fellowship – Child and Adolescent Psychiatry
    University of Florida
  • 1987
    Residency – Psychiatry
    University of Florida
  • 1981
    Medical Degree
    Justin-Liebig-Universitat
Lance McMahon

Lance McMahon Ph.D., M.S.

Chair And Professor
Department: Pharmacodynamics
Phone: (352) 294-8878

Dr. McMahon is Professor and Chair of the Department of Pharmacodynamics at the University of Florida College of Pharmacy. He previously held the position of Tenured Associate Professor of Pharmacology at the University of Texas Health Science Center in San Antonio. He obtained a PhD in Behavioral Neuroscience from Texas A&M University, and was a postdoctoral fellow in the Department of Pharmacology and Toxicology at the University of Texas Medical Branch in Galveston. He has been continuously funded by the National Institute on Drug Abuse since 2002 as PI of 6 R01 grants, an R21, and a U grant for a total of $22M in funding. He is a regular member of the Center for Scientific Review NIH study section Biobehavioral Regulation, Learning and Ethology. He served on the Executive Board of the Behavioral Pharmacology Division of the American Society of Pharmacology and Experimental Therapeutics. Dr. McMahon’s laboratory integrates principles of behavior and receptor theory to identify CNS mechanisms responsible for drug dependence, and novel pharmacological strategies that maximize therapeutics and minimize abuse liability.

Accomplishments:
  • Scientific Programming Committee
    2019-2020 · American Association of Pharmaceutical Scientists
  • Guest Editor
    2019-2020 · Pharmacology Biochemistry and Behavior
  • Internal Scientific Advisory Committee
    2018-Current · Center for Addiction Research and Education
  • Executive Committee
    2018-Current · UF Health Neuroscience and Neuromedicine Research
  • Regular Member, Biobehavioral Regulation Learning and Ethology Study Section
    2017-2021 · NIH Center for Scientific Review
  • Executive Board
    2017-2018 · Texas Research Society on Alcoholism
  • Executive Committee
    2009-2011 · Division of Behavioral Pharmacology, American Society of Pharmacology and Experimental Therapeutics
  • Scientific Programming Committee
    2008-2011 · College on Problems of Drug Dependence
  • Field Editor
    2006-2017 · International Journal of Neuropsychopharmacology
Research Summary:

Research in my laboratory integrates principles of behavior and receptor theory to identify central nervous system mechanisms responsible for drug dependence. We also investigate novel pharmacological strategies that maximize therapeutic potential and minimize abuse and dependence liability. We combine behavioral and physiological approaches, receptor-selective ligands, and quantitative analyses of drug interactions. We are interested in several pharmacological classes of abused drugs.

Cannabinoids, for example, include cannabis-derived tetrahydrocannabinols, numerous synthetic cannabinoids, and endogenous cannabinoid neurotransmitters. We systematically compare the effects of cannabinoids and evaluate underlying receptor mechanisms to better understand dependence and therapeutic potential.

Cholinergic drugs of interest include FDA-approved smoking cessation aids such as nicotine, varenicline, and bupropion. We compare the effects of smoking cessation aids and investigational nicotinic acetylcholine receptor drugs to better understand relationships between nicotinic acetylcholine receptor subtypes, intrinsic activity (i.e., efficacy), and behavioral effects. Most recently, we are joining investigators in the Departments of Medicinal Chemistry (McCurdy), Pharmaceutics (Avery), and Pharmacodynamics (McLaughlin, Peris) to evaluate the in vitro and in vivo pharmacology of kratom and its derivatives which have proven therapeutic utility in the reduction of opioid dependence.

Research Interests:
  • Behavioral pharmacology
Publications:
Grants:
  • May 2021 ACTIVE
    Behavioral Pharmacology of SBS Compound in Rats
    SPARIAN BIOSCIENCES · Principal Investigator
  • Dec 2020 ACTIVE
    Opioid use disorders: UF Pharmacy medications discovery and development
    NATL INST OF HLTH NIDA · Principal Investigator
  • Jun 2019 ACTIVE
    Opioid and cannabinoid interactions in pain and reward
    UF RESEARCH · Co-Investigator
  • Apr 2019 ACTIVE
    Kratom alkaloids: in vitro and in vivo pharmacological mechanisms
    NATL INST OF HLTH NIDA · Principal Investigator
  • Dec 2018 – Nov 2020
    Opioid use disorders: UF Pharmacy medications discovery and development
    NATL INST OF HLTH NIDA · Principal Investigator
  • Oct 2017 – Jun 2019
    Nicotine dependence: neuropharmacology in monkeys
    NATL INST OF HLTH NIDA · Principal Investigator
Education:
  • 1997
    Ph.D.
    Texas A&M University
  • 1994
    M.S.
    Texas A&M University
  • 1992
    B.A.
    University of Pennsylvania

 

Community Members:

Carson Pennypacker, LCSW
Carson Pennypacker, LCSW (Bio)
Director of Substance Use Recovery Program
Meridian Behavioral Healthcare
Leanetta McNealy
Leanetta McNealy, Ph.D. (Bio)
School Board Member
Alachua County Public Schools

External Advisory Committee:

Howard Becker
Howard Becker, Ph.D. (bio)
Director, Charleston Alcohol Research Center
Professor, Department of Psychiatry & Behavioral Sciences
Medical University of South Carolina
Kathleen Grant
Kathleen A. Grant, Ph.D. (bio)
Professor & Chief, Division of Neuroscience
Oregon National Primate Research Center
Oregon Health & Science University
Stephanie O'Malley
Stephanie O’Malley, Ph.D. (bio)
Professor of Psychiatry
Director, Division of Substance Abuse Research in Psychiatry
Deputy Chair, Clinical Research
Yale School of Medicine

Committee Chairs:

Executive Committee: Marieta Heaton, Ph.D.

Annual Symposium Committee: Barry Setlow, Ph.D. & Ben Lewis, Ph.D. (Co-Chairs)

Travel Awards Committee: Marieta Heaton, Ph.D. & Catherine Striley , Ph.D., MSW, ACSW, MPE (Co-Chairs)

Seminar Committee: Marek Schwendt, Ph.D. & Meredith Berry, Ph.D. (Co-Chairs)

Social Events Committee: Robert Leeman, Ph.D. & Jeff Boissoneault, Ph.D. (Co-Chairs)